The Pharmacodynamics of L-Arginine
نویسندگان
چکیده
منابع مشابه
The Pharmacodynamics of L - Arginine 1 – 3
L-Arginine is a precursor for nitric oxide (NO) synthesis. NO is a ubiquitous mediator that is formed by a family of enzymes named NO synthases. In the brain, NO acts as a neurotransmitter; in the immune system, NO acts as a mediator of host defense; and in the cardiovascular system, NO mediates the protective effects of the intact endothelium, acting as a vasodilator and endogenous antiatherog...
متن کاملL-Arginine Monograph
Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...
متن کاملL-Arginine Metabolic Pathways
The present review will give an overview of the biochemistry and metabolism of L-arginine focusing on the mechanisms which may either provide or limit cellular availability of this amino acid for nitric oxide synthases and arginase / polyamine pathway and describe possible interactions between these pathways. In addition, emerging species differences in the expression and role of arginases are ...
متن کاملMonograph - L-Arginine
Introduction L-Arginine is a semi-essential amino acid involved in numerous areas of human physiology, including production of nitric oxide (NO) – a key messenger molecule involved in vascular regulation, immune activity, and endocrine function. Arginine is also involved in protein production, wound healing, erectile function, and fertility. Arginine is not considered essential because humans c...
متن کاملThe effect of L-arginine and L-NAME on intravenous self-administration of morphine in rats
The involvement of nitric oxide (NO) in the reinforcing properties of opiate reward was studied by examining the effect of a NO precursor (L-arginine) and a NO synthase inhibitor (L-NAME) on the rate of intravenous self-administration of morphine. This experiment was investigated in male albino Sprague Dawley rats (300 ± 50 g). At doses of 5 and 10 mg/kg (i.p.), L-arginine decreased morphine ...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2007
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/137.6.1650s